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Thursday, April 30, 2026

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A Fascinating Paradox Regarding Vitamin, Illness Threat, And Survival – BionicOldGuy


Dr. Raphael Cuomo, a professor on the College of California, San Diego College of Drugs who’s work I’ve talked about beforehand, referred to as my consideration to an enchanting current paper he wrote. It’s about “dietary epidemiology threat–survival paradox”, for which the time period “Cuomo’s Paradox” has additionally been coined. There’s additionally a superb abstract of the paradox in this youtube video. To summarize, there are well being and vitamin suggestions to scale back the danger of buying situations like heart problems and sure kinds of most cancers. However the paradox is that if you have already got one in every of these ailments, these identical suggestions can grow to be contraindicated as a result of they’ll now improve the danger of dying from the illness. An vital exemple is weight problems, which is effectively often known as a threat issue. However carrying some further kilos could be protecting after you have already got a illness.

Instance of Cuomo’s Paradox: Impact of being chubby, consuming alcohol, and ldl cholesterol on affected person’s with coronary heart failure (https://www.youtube.com/watch?v=qW_Q09R0ON0)

Proof for extra results like this (like the consequences of alcohol and ldl cholesterol) are lined within the paper. Dr. Cuomo is cautious to level out that we might not but have sufficient data to alter well being suggestions, however extra analysis is certainly wanted on this intriguing paradox. Here’s a hyperlink to the complete textual content within the Journal of Vitamin.



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