Welcome to Ben Greenfield’s Weekly Roundup!
On this weekly put up, I share with you my most attention-grabbing discoveries of the week, together with the newest information on the fronts of health, diet, well being, wellness, biohacking, and anti-aging analysis. I additionally recap my upcoming occasions and particular bulletins so you may sustain with alternatives to be taught, giveaways, reductions, and extra!
New Discoveries
Assume Creatine Stops Working After “Beginner Beneficial properties”? *This* NEW Information Suggests In any other case… 💪🔥🧠
You may assume that when you’ve been lifting for years, dietary supplements like creatine cease making a significant distinction. Or that in the event you’re not a newbie, the “simple positive factors” are gone and also you’re by yourself.
Two latest giant meta-analyses counsel in any other case.
A 2025 systematic assessment, which pooled information from 61 managed trials, discovered that creatine mixed with resistance coaching considerably elevated fat-free mass by a mean of 1.39 kg (or simply above 3 lbs), with out growing fats mass.
Importantly, each novice and skilled lifters benefited. Skilled individuals truly confirmed about 0.6 kg (1.32 lbs) better positive factors in lean mass in comparison with novices, although the distinction wasn’t statistically important.
Translation: creatine nonetheless strikes the needle even if you’re effectively previous your first yr within the health club.

One other 2025 meta-analysis targeted particularly on energy outcomes and located that creatine considerably improves muscle energy throughout the overall inhabitants, together with individuals of all ages and coaching backgrounds. Apparently, untrained adults tended to see bigger relative energy jumps, however educated lifters nonetheless gained meaningfully.
The simplest technique? Low-to-moderate dosing mixed with high-intensity coaching. Larger doses didn’t outperform reasonable ones, and more durable coaching amplified the impact.
What these two research reveal is that creatine is not only a “newbie complement,” neither is it a blunt mass-gain software. It’s a efficiency amplifier, it doesn’t matter what your age or health degree.
By growing intramuscular phosphocreatine, creatine enhances your skill to regenerate ATP throughout quick, explosive efforts. Meaning extra high quality reps, better whole coaching quantity, and stronger neural output over time. The brand new information reinforce that dosing and coaching depth matter greater than megadosing or fancy loading schemes.
Virtually talking, 3 to five grams every day stays a wise baseline for most individuals, though as much as 10 grams/day might be helpful for some relying on their physique dimension and health objectives. Pair creatine with progressive, high-intensity resistance coaching, keep constant, and let the compound impact accumulate.
If you would like a deeper dive into creatine timing (together with how I personally use it on daily basis), loading protocols, cognitive advantages, and the way it matches right into a broader muscle-building or longevity plan, you may take a look at the hyperlinks under:
- The Dust Low-cost, Extensively Out there Pure Molecule That Is One Of The Most Effectively-Researched Dietary supplements For Cognition, Muscle Restore, Endurance, Testosterone & A lot Extra.
- Is Too A lot Protein Dangerous For You? The TRUTH About Creatine, What’s The “Healthiest” Alcohol & Extra! Solosode #480.
- Can This Low-Price, Extremely-Researched, Extremely Secure Peptide Assist You Sleep Much less and Not Pay For It Later? (Plus 6 Methods to Mitigate the Results of Sleep Deprivation).
- Ben Greenfield’s Sport-Altering Biohacks & Well being Developments of 2025: 10 Science-Backed Methods For Revolutionizing Human Efficiency.
- Microplastics In Glass Bottles & Lead In Salt? Cardio Earlier than Energy Or Energy Earlier than Cardio? Creatine Causes Hair Loss? & Extra: Solosode #492.
- How To Get The Most Bang For Your Buck From Restoration, Dietary supplements, Vitamin, Psychological Coaching & Race Prep.
- The Final Information To Sustaining Muscle (Even When You Can’t Exercise).
Thrilling Announcement: I’ve Partnered with Subsequent Well being to Assist Scale the Way forward for Longevity Medication 🧠⚡
A number of years in the past, I visited a cutting-edge well being and biohacking clinic at a high-end mall in Los Angeles that felt like stepping onto the deck of a spaceship.
I used to be like a child in a sweet retailer exploring their superior therapies, together with cryotherapy, pink mild beds, hard-shell hyperbaric chambers,
an intensive IV remedy menu, and far more.
Quick ahead to at present, and Subsequent Well being has expanded globally. Its forward-thinking longevity and well being optimization clinics can now be present in cities together with Nashville, Miami, Dubai, and several other different areas.
You’ll have even seen the founder, Dr. Darshan Shah, within the latest Liquid Dying power drink “exploding heads” Tremendous Bowl business.
I’m excited to share that I’ve formally joined the Subsequent Well being Scientific Advisory Council on the invitation of Dr. Shah.
I’ve identified him for years, and he’s not only a surgeon turned longevity pioneer. He understands that our present healthcare mannequin is essentially reactive, fragmented, and targeted on symptom administration slightly than restoring power, sharpening cognition, enhancing physique composition, and lengthening lifespan.
Dr. Shah is constructing Subsequent Well being as a scalable system designed to maintain individuals resilient and proactive about their well being, and I’m honored to help that imaginative and prescient.
With greater than 100 areas deliberate, the purpose is to create a real medical follow rooted in longevity science and root-cause medication, deployed at scale throughout america and ultimately worldwide.
As a part of the Scientific Advisory Council, I’ll work alongside the Subsequent Well being crew to develop science-based protocols geared toward rebuilding metabolic perform, optimizing hormones, enhancing restoration capability, and addressing the continual patterns that undermine high quality of life.
I stay up for sharing extra about what we’re constructing and the way this mannequin continues to evolve within the months forward. To find extra, you may go to an area Subsequent Well being clinic or discover areas right here at Subsequent-Well being.com.
This Week in Well being & Efficiency: What the Newest Analysis Says
🔥 Amino Acid Restriction Mimics Chilly Publicity: New analysis in mice discovered that reducing dietary methionine and cysteine considerably elevated calorie burning and weight reduction, producing metabolic results much like chilly publicity. This implies that periodic reductions in animal protein or particular amino acids might stimulate fats loss pathways. One doable technique? An occasional protein-restricted day mixed with cardio train (learn extra right here).
☕ Caffeine’s Energy Increase Relies on Your Genes: A latest examine discovered that caffeine improves energy coaching efficiency primarily in individuals with particular variants of the CYP1A2 gene (AC or AA genotype). In different phrases, your genetic make-up might decide whether or not caffeine acts as a strong ergogenic help or only a gentle pick-me-up earlier than a exercise (full examine right here).
🦠 Intermittent Fasting Could Calm Irritable Bowel Signs: Analysis means that giving your digestive system periodic breaks by means of intermittent fasting might assist cut back signs related to irritable bowel points. These fasting home windows might help intestine motility, microbial stability, and digestive restoration (learn the examine).
Key Takeaway: Strategic metabolic stressors—like amino acid restriction, focused caffeine use, and intermittent fasting—might present highly effective instruments for enhancing fats loss, efficiency, and digestive well being when utilized thoughtfully.
Need to dive deeper? Click on the hyperlinks above to discover the analysis, and click on right here to observe me on X for all the newest well being and efficiency information sizzling off the press!
Product Of The Week
::: Cease Cooking with Toxins—Save 10% on Eternally Chemical-Free Cookware :::
In case you care about what goes into your meals, you must also care about what you are cooking on.
The fact is that almost all conventional nonstick cookware nonetheless comprises PFAS, the so-called “perpetually chemical substances” present in Teflon that may leach into your meals, your own home, and finally your physique. 
Latest analysis exhibits that even a single scratch on a typical nonstick pan can launch round 9,100 microplastic particles. That’s a every day poisonous publicity most individuals by no means even take into account.
That’s one purpose I switched to Our Place. Their cookware is totally toxin-free, with no PFAS, no PTFEs, and no hidden chemical coatings, simply high-performance supplies designed for protected, on a regular basis cooking.
In case you’re able to improve your kitchen intelligently, the Our Place 4-Piece Cookware Set is among the easiest and smartest methods to do it.
It consists of:
- 2 All the time Pans (Full + Mini)
- 2 Excellent Pots (Full + Mini)
With simply 4 multifunctional items, you may:
- Sear
- Sauté
- Fry
- Bake
- Boil
- Roast
- Steam
…and change a whole cluttered cupboard of mismatched pots and pans.
In case you’re able to cease cooking with questionable cookware and improve your kitchen, head right here and use code BEN for 10% off sitewide.
With a 100-day risk-free trial, free delivery, and free returns, you may do this game-changing cookware with zero danger.
Podcasts I Recorded This Week:


The Newest Content material I Was Featured On This Week:
Biohacking the Vagus Nerve f. Ben Greenfield — The Well being Improve Podcast
Ben Greenfield on Elevating Wholesome Youngsters, Being pregnant Health, and Dad Preparation
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