Welcome to Ben Greenfield’s Weekly Roundup!
On this weekly submit, I share with you my most attention-grabbing discoveries of the week, together with the newest information on the fronts of health, vitamin, well being, wellness, biohacking, and anti-aging analysis. I additionally recap my upcoming occasions and particular bulletins so you possibly can sustain with alternatives to be taught, giveaways, reductions, and extra!
New Discoveries
Really feel “Bizarre” Throughout NAD IV Remedy? *These* 3 Suggestions From a Regenerative Drugs Pioneer Make Your Therapy Smoother, Quicker & Extra Efficient ⚡
When you’ve spent any time round longevity clinics, restoration facilities, or high-performance circles these days, you have most likely seen individuals hooked as much as an NAD IV.
NAD (nicotinamide adenine dinucleotide) is without doubt one of the most essential molecules within the physique for turning meals into power and powering mobile restore, which is why these infusions are used to spice up power manufacturing, psychological readability, restoration, mitochondrial well being, wholesome growing old, and even resilience after journey, stress, or overtraining.
The factor about NAD infusions is that they’ll really feel intense. Some individuals expertise nausea, flushing, chest stress, restlessness, or an odd “one thing feels off” sensation throughout the drip. It is why some who attempt it by no means return.
Luckily, there are methods to make the method a lot smoother, together with these methods from regenerative drugs pioneer (and this Saturday’s podcast visitor), Dr. Joseph Purita.
1. Take TMG Earlier than Your Infusion
TMG (trimethylglycine), also called betaine, acts as a methyl donor. Throughout NAD infusions, your physique produces nicotinamide (NAM), which should be cleared effectively by way of methylation by an enzyme referred to as NNMT (nicotinamide N-methyltransferase). This course of consumes methyl teams and may briefly elevate homocysteine, which alerts that methylation pathways have gotten depleted, lowering the physique’s capacity to clear nicotinamide effectively and contributing to unintended effects. Taking TMG beforehand might assist help methylation pathways and enhance tolerance.
2. Sip Espresso Throughout The IV
This one surprises individuals. The caffeine in espresso can probably upregulate NMNAT2 (nicotinamide mononucleotide adenylyltransferase 2), a key enzyme concerned in recycling NAD precursors again into usable NAD+. Caffeine additionally blocks adenosine receptors, which can assist scale back a few of the sluggish or uncomfortable sensations individuals expertise throughout infusions.
3. Use Crimson Gentle To Photoactivate The NAD
One other superior technique Dr. Purita makes use of at PUR-FORM is exposing the NAD answer to pink gentle earlier than it enters the IV bag. This could improve manufacturing of NADH, the decreased type of NAD, which may then be quickly recycled again into NAD+ by way of mitochondrial advanced I to help mobile power manufacturing.
My take is that NAD IVs generally is a implausible instrument, however the supply course of makes a giant distinction within the outcomes.
When you’ve struggled with unintended effects or wish to get extra from the expertise, these three easy tweaks would possibly make all of the distinction.
If you wish to go deeper on NAD, superior therapies like IVs, and different regenerative drugs protocols, you possibly can try the assets beneath (and do not forget to tune into Saturday’s present with Dr. Purita by subscribing to my podcast on Spotify, Apple Podcasts, or YouTube):
- Every thing You Want To Know About NAD+: The Essential Position It Performs In Your Mitochondrial Well being, How NAD+ Slows Down Ageing & Will increase Power, Methods To Improve NAD+ Utilizing Way of life, Why NAD+ Precursors Might Be Problematic & A Secure, Value-Efficient Oral NAD+ Complement Technique.
- The NAD Supersode: All Ben’s Loopy Questions About NAD, Pure Methods To Improve NAD, Residing To 120 With NAD & A lot Extra With Matt Titlow & Michael Roberts.
- May NAD IVs Be Unhealthy For You (& How To Increase NAD Naturally), With Dr. Nichola Conlon.
- The AMAZING Future Of Regenerative Drugs, The New Sexier Various To Stem Cells, The place You Ought to Get Peptides (& The Greatest Peptides Stacks) & Extra With Dr. Matt Prepare dinner.
- Peptides, Biologics & Small Molecules You’ve *By no means Heard Of* For Sleep, Mitochondria, Kidney Well being & Extra, With Jim LaValle.
- Ben Greenfield’s Recreation-Altering Biohacks & Well being Tendencies of 2025: 10 Science-Backed Methods For Revolutionizing Human Efficiency.
- ONE Tiny Blood Spot = HUNDREDS (!) Of Biomarkers, Age & Illness Prediction With Dr. Matt Dawson.
Your 2026 Mom’s Day Reward Information Has Arrived! I Hand-Picked These Items for Your Mother (+ Laser Lights & EXOSOMES?!) 🩷
Panicking over what to get Mother this Mom’s Day and do not know the place to start out, or simply don’t wish to give her one other *boring* present this yr?
Skip the same old suspects: flowers that fade inside three days, candles that shortly burn out, and tub bombs that stain your bathtub cotton sweet blue.
The particular lady in your life deserves one thing unbelievable that *truly* lasts. I imply, she modified your diapers, proper?
So… I put collectively my 2026 Mom’s Day Reward Information with one factor in thoughts: serving to you give Mother a vetted current that delivers her recent power, higher restoration, unparalleled sleep, and long-term well being.
🎁 Only a few highlights from the information:
- Sunlighten mPulse Sauna: Customized infrared sauna periods for restoration, rest, detox, and deeper sleep.
- Apollo Neuro: A wearable designed to help calm, stress resilience, and higher sleep.
- Younger Goose Reward Units: Superior skincare protocols targeted on restore, mobile power, and pores and skin longevity.
- Pendulum Metabolic Day by day: Clinically studied probiotics for intestine well being, metabolism, and regular power.
- LIFEprint HTMA Take a look at: At-home testing to show hidden mineral imbalances, stress patterns, and power roadblocks.
- Boundless: My bestselling well being optimization e book filled with methods for hormones, metabolism, longevity, and peak efficiency.
So, what are you ready for?
Scroll by way of, discover Mother a memorable present, and use the low cost codes listed within the information for further financial savings on these time-sensitive offers.
👉 Seize the Good Reward for Mother
This Week in Well being & Efficiency: What the Newest Analysis Says
💪⏳ Fasting & Muscle Loss—Not So Quick: Sure, fasting can contribute to muscle loss, however analysis exhibits resistance coaching dramatically improves your capacity to protect lean mass, even on fasting days. The lesson: in case you quick, elevate (learn the research).
🌙📉 Easy Meal Timing for Higher Metabolic Well being: When you wrestle with blood sugar swings, cussed physique fats, low HRV, or elevated resting coronary heart fee, one of many easiest interventions could also be avoiding meals for roughly 3 hours earlier than mattress and delaying your first meal for just a few hours after waking. Circadian-aligned consuming continues to point out highly effective advantages (full research right here).
🐟🧠 What Is “Sardinemaxxing”?: The web’s newest vitamin development focuses on consuming extra sardines for his or her wealthy provide of omega-3s, protein, calcium, selenium, and low-mercury comfort. Odd identify, however nonetheless a sensible meals (learn extra).
🏆💉 The “Enhanced Video games” Debate Heats Up: A provocative new tackle the drug-permitted “Enhanced Video games” raises questions on ethics, athlete well being, and the place the way forward for elite sport could also be heading. Whether or not you see progress or insanity, it’s price paying consideration (get the total story).
Key Takeaway: This week’s analysis factors to a well-known reality: fundamentals nonetheless win. Elevate weights in case you quick, align meals with circadian rhythms, eat nutrient-dense entire meals, and be cautious every time shortcuts promise superhuman efficiency.
Wish to dive deeper? Click on the hyperlinks above to discover the analysis, and click on right here to comply with me on X for all the newest well being and efficiency information scorching off the press! 
Product Of The Week
::: Take in Your Weight-reduction plan’s Vitamins Higher With BIOptimizers MassZymes (& Save 15%) :::
You’ve heard, “You’re what you eat…”
However the actual reality is that you’re what you take up, and even the cleanest, most nutrient-dense eating regimen can fall quick in case your digestion is not optimized.
Enzyme manufacturing naturally declines with age, stress, journey, and laborious coaching, which suggests you possibly can be extracting far much less vitamin out of your meals than you assume, impacting your restoration, power, muscle constructing, and total efficiency.
That is the place BIOptimizers MassZymes is available in.
It is a full-spectrum digestive enzyme components containing 322,000 HUTs of protease, the highest-potency enzyme that helps break down protein into usable amino acids.
Higher digestion means improved nutrient uptake, much less bloating, quicker restoration, and extra return from each chew you eat.
Prepared to truly use what you eat?
You possibly can snag 15% off MassZymes with code BEN15 at checkout right here.
Podcasts I Recorded This Week:
May NAD IVs Be Unhealthy For You (& How To Increase NAD Naturally), With Dr. Nichola Conlon
How To Be A Higher, Extra Current Father (& Not Get DAD-BOD!) with John Schott
The Newest Content material I Was Featured On This Week:
My Article Feed:
My full article feed and all archives of my articles are right here.
Upcoming Occasions:
ECO26 | Might 14–16, 2026
Healthcare practitioners seeking to obtain exponential scientific outcomes by way of Foundational Drugs: I am talking at ECO26 (Might 14–16, 2026, in Boise, ID), a three-day occasion that includes cutting-edge training, highly effective networking, and actionable methods to raise your observe (with as much as 20 CEUs out there for some practitioner varieties). I will be presenting “The Detox Frontier: Classes from The Edges of Biohacking to On a regular basis Vitality” on Might fifteenth alongside a few of the prime minds in purposeful and foundational drugs. You possibly can use this hyperlink to register and declare a $400 low cost!
Final Males Over 40 Well being Summit | June 8–14, 2026
When you’re a person over 40 seeking to enhance your power, power, well being, hormones, restoration, longevity, and efficiency, I am talking on the Final Males Over 40 Well being Summit (June 8–14, 2026), a free 7-day digital occasion that includes 100+ specialists throughout 7 core pillars. I will be presenting “Optimizing the Human Machine for 40 and Past” alongside a few of the finest minds in males’s well being immediately. You possibly can register free of charge right here now!
Well being Optimisation Summit | September 11–13, 2026
I am talking on the Well being Optimisation Summit in London (September 11–13, 2026) on the Enterprise Design Centre. This is not your common well being convention. HOS unites the most effective minds in biohacking, longevity, vitamin, health, and drugs, with one purpose: to truly make individuals more healthy. With 35+ world-class audio system, 120+ cutting-edge manufacturers, and 4,000 like-minded individuals all beneath one roof, it is two days that would genuinely change the way you strategy your well being. Get your ticket right here and use code BEN to save lots of 10% off registration!
Eudēmonia | November 5–8, 2026
I am talking at Eudēmonia (November 5–8, 2026, in West Palm Seaside, FL), a prevention-focused, science-based well being, well-being, and longevity summit designed so as to add years to your life and life to your years. Throughout 3 days and 15 venues, you will expertise 200+ talks from 120+ specialists, 300 therapies, and 160+ manufacturers overlaying all the things from biohacking, longevity, and hormonal well being to intestine well being, mind well being, peptides, mobility, and extra. I will be main a chat and a motion session alongside a few of the brightest minds in well being immediately. Use code BGREENFIELD-EUD-100 for $100 off if you register right here!
The Boundless {Couples} Retreat | November 10–14, 2026
Able to reconnect and recharge together with your accomplice in paradise? Be part of the Greenfields on the gorgeous Prana Maya resort in Belize for the Boundless {Couples} Retreat, November 10–14, 2026. It is a five-day, all-inclusive escape designed to deepen your relationship, restore your vitality, and create recollections that final a lifetime. From rest and journey to intimate relationship teaching with Jessa and me, each element is crafted to ship you dwelling with a stronger bond and a reinvigorated spirit. Spots are restricted, so uncover extra and safe yours right here immediately!
Keep tuned for future updates—and you may at all times sustain with my LIVE appearances by testing bengreenfieldlife.com/calendar!
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Cheers,
Ben
